Abstract:

The compatibility between active pharmaceutical ingredients (APIs) and excipients plays a pivotal role in the formulation development process, influencing drug stability, efficacy, and bioavailability. This research paper provides an extensive review of the recent advances in analytical techniques employed for studying drug-excipient compatibility. The paper discusses various instrumental methods, including spectroscopic, chromatographic, thermal, and microscopy-based approaches, highlighting their applications, advantages, and limitations. Additionally, case studies illustrating the successful implementation of these techniques in the pharmaceutical industry are presented. The integration of these advanced analytical tools offers a comprehensive understanding of drug-excipient interactions, ultimately enhancing the quality and performance of pharmaceutical formulations

Description:

drug-excipient compatibility, analytical techniques, spectroscopy, chromatography, microscopy