Abstract:

The study investigates the synthesis, characterization, and antimycobacterial activity of Copper (II)-Ciprofloxacin complexes. These complexes were synthesized through the reaction of ciprofloxacin with copper salts under controlled conditions. Comprehensive characterization was performed using a variety of techniques including UV-Vis spectroscopy, IR spectroscopy, and nuclear magnetic resonance (NMR) spectroscopy, which confirmed the formation of the complexes and provided insights into their structural properties. X-ray crystallography was employed to determine the precise molecular and crystal structure of the complexes, revealing detailed geometric configurations and bond parameters. The antimycobacterial efficacy of the synthesized complexes was evaluated against Mycobacterium tuberculosis strains, showing significant activity and suggesting potential for therapeutic applications. This study demonstrates that the incorporation of copper into ciprofloxacin enhances its antimycobacterial properties, offering a promising avenue for the development of more effective antimicrobial agents.

Description:

Compound, Bacteria, antibacterial, molecules